Water → Ethyl 4-acetoxybenzoylformate

HRID 1901328노트

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HRID 1901328 반응식
[OH:1][C:2]1[CH:7]=[CH:6][C:5]([C:8](=[O:14])[C:9]([O:11][CH2:12][CH3:13])=[O:10])=[CH:4][CH:3]=1.[C:15](OC(=O)C)(=[O:17])[CH3:16].O>N1C=CC=CC=1>[C:15]([O:1][C:2]1[CH:3]=[CH:4][C:5]([C:8](=[O:14])[C:9]([O:11][CH2:12][CH3:13])=[O:10])=[CH:6][CH:7]=1)(=[O:17])[CH3:16]

참가 물질

5

반응물 3

HCID 962WaterHCID 7918Acetic AnhydrideHCID 11715332Ethyl 2-(4-hydroxyphenyl)-2-oxoacetate

생성물 1

HCID 10977426Ethyl 4-acetoxybenzoylformate

시약·촉매·용매 1

HCID 1049Pyridine용매

실험 절차

7.25 g of ethyl 2-(4-hydroxyphenyl)-2-oxoacetate was dissolved in 15 ml of pyridine, followed by adding 4 ml of acetic anhydride and then stirring at room temperature for 1 hour. The resulting reaction solution was poured into water, and extracted with diethyl ether. The resulting organic layer was washed with water, and then concentrated to dryness. Thereafter, the residue was dissolved in benzene, and then concentrated to obtain 8.3 g of the title compound in an oily form.

후처리

  1. customThe resulting reaction solution
  2. extractionextracted with diethyl ether
  3. washThe resulting organic layer was washed with water
  4. concentrationconcentrated to dryness
  5. dissolutionThereafter, the residue was dissolved in benzene
  6. concentrationconcentrated

출처 및 근거

ORD 기록
ord-a0f15ccff79f44a39c912aebc87f743f
출처 데이터셋
uspto-grants-1996_11
특허 번호
US05576343

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