Diclofenac sodium → HCID 54029926, 화합물

HRID 1902340

반응식

HRID 1902340 반응식
[Cl:1][C:2]1[CH:7]=[CH:6][CH:5]=[C:4]([Cl:8])[C:3]=1[NH:9][C:10]1[CH:15]=[CH:14][CH:13]=[CH:12][C:11]=1[CH2:16][C:17]([O-:19])=[O:18].[Na+].[NH2:21][C:22]1[C:39]([CH2:40][N:41]([CH:44]2[CH2:49][CH2:48][CH2:47][CH2:46][CH2:45]2)[CH2:42][CH3:43])=[CH:38][C:25]([C:26]([O:28][CH2:29][CH2:30][N:31]([CH:35]([CH3:37])[CH3:36])[CH2:32][CH2:33]Cl)=[O:27])=[CH:24][C:23]=1[Br:50]>>[NH2:21][C:22]1[C:39]([CH2:40][N:41]([CH:44]2[CH2:49][CH2:48][CH2:47][CH2:46][CH2:45]2)[CH2:42][CH3:43])=[CH:38][C:25]([C:26]([O:28][CH2:29][CH2:30][N:31]([CH:35]([CH3:36])[CH3:37])[CH2:32][CH2:33][O:18][C:17](=[O:19])[CH2:16][C:11]2[CH:12]=[CH:13][CH:14]=[CH:15][C:10]=2[NH:9][C:3]2[C:2]([Cl:1])=[CH:7][CH:6]=[CH:5][C:4]=2[Cl:8])=[O:27])=[CH:24][C:23]=1[Br:50]

참가 물질

3

반응물 2

HCID 5018304Diclofenac sodiumHCID 20516495N-{2-[4-amino-3-bromo-5-(N-ethyl-cyclohexylaminomethyl)-benzoyloxy]-ethyl}-N-(2-chloroethyl)-isopropylamine

생성물 1

HCID 54029926HCID 54029926, 화합물

실험 절차

This compound was prepared from sodium 2-[(2,6-dichlorophenyl)-amino]-phenyl-acetate and N-{2-[4-amino-3-bromo-5-(N-ethyl-cyclohexylaminomethyl)-benzoyloxy]-ethyl}-N-(2-chloroethyl)-isopropylamine analogous to Example 8. Oil.

출처 및 근거

ORD 기록
ord-ca5fae7a2cbb4b8780ffc984ac4b15f6
출처 데이터셋
uspto-grants-1982_12
특허 번호
US04362738

연결된 노트

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