Hydrochloric Acid → HCID 20515751, 화합물

HRID 1902535노트

반응식

HRID 1902535 반응식
C[Si](C)(C)[O:3][C:4]1([C:7]([O-:9])=[O:8])[CH2:6][CH2:5]1.Cl.[C:13]1(C)[CH:18]=CC=C[CH:14]=1>>[CH:13]([CH:5]1[CH2:6][C:4]1([OH:3])[C:7]([OH:9])=[O:8])([CH3:18])[CH3:14]

참가 물질

4

반응물 3

HCID 313Hydrochloric AcidHCID 1140TolueneHCID 131712897HCID 131712897, 화합물

생성물 1

HCID 20515751HCID 20515751, 화합물

실험 절차

17.0 g (0.06 mole) of trimethylsilyl 2-isopropyl°-1-trimethylsiloxy-cyclopropanecarboxylate were stirred for 2 hours at 30° C. in 100 ml of toluene saturated with hydrogen chloride. Dry nitrogen was then passed through the solution for 1 hour and the precipitate was filtered off. Crystallization from xylene yielded 2-isopropyl-1-hydroxycyclopropanecarboxylic acid (6.1 g) with a melting point of 135° to 138° C.

후처리

  1. filtrationthe precipitate was filtered off
  2. customCrystallization from xylene

출처 및 근거

ORD 기록
ord-062bc64a85ac49928f946dc717f89a44
출처 데이터셋
uspto-grants-1982_12
특허 번호
US04363926

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