3-Chlorothieno[3,2-b]pyridine-5,6-dicarboxylic acid → 3-Chlorothieno[3,2-b]pyridine-5,6-dicarboxylic acid anhydride
반응식
[Cl:1][C:2]1[C:6]2=[N:7][C:8]([C:14]([OH:16])=[O:15])=[C:9]([C:11]([OH:13])=O)[CH:10]=[C:5]2[S:4][CH:3]=1>C(OC(=O)C)(=O)C>[Cl:1][C:2]1[C:6]2=[N:7][C:8]3[C:14](=[O:15])[O:16][C:11](=[O:13])[C:9]=3[CH:10]=[C:5]2[S:4][CH:3]=1참가 물질
3
실험 절차
3-Chlorothieno[3,2-b]pyridine-5,6-dicarboxylic acid (1.45 g) is heated at 85° to 90° C. for 30 minutes then 90° to 102° C. for 30 minutes in acetic anhydride (7 mL). The reaction is cooled, the solids filtered off and washed with ether to give 1.2 g of 3-chlorothieno[3,2-b]pyridine-5,6-dicarboxylic acid anhydride. The proton magnetic resonance spectrum is consistant with the structure.
후처리
- temperatureThe reaction is cooled
- filtrationthe solids filtered off
- washwashed with ether
출처 및 근거
- ORD 기록
- ord-c104cae14b824a67b426c156a726c791
- 출처 데이터셋
- uspto-grants-1987_03
- 특허 번호
- US04650514
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