1-(2-Methoxyphenyl)piperazine → HCID 13729383, 화합물

HRID 1906438

반응식

HRID 1906438 반응식
[C:1]([C:4]1[O:5][C:6]2[C:12]([O:13][CH2:14][CH:15]3[O:17][CH2:16]3)=[CH:11][CH:10]=[CH:9][C:7]=2[CH:8]=1)(=[O:3])[NH2:2].[CH3:18][O:19][C:20]1[CH:25]=[CH:24][CH:23]=[CH:22][C:21]=1[N:26]1[CH2:31][CH2:30][NH:29][CH2:28][CH2:27]1>C(O)C>[C:1]([C:4]1[O:5][C:6]2[C:12]([O:13][CH2:14][CH:15]([OH:17])[CH2:16][N:29]3[CH2:28][CH2:27][N:26]([C:21]4[CH:22]=[CH:23][CH:24]=[CH:25][C:20]=4[O:19][CH3:18])[CH2:31][CH2:30]3)=[CH:11][CH:10]=[CH:9][C:7]=2[CH:8]=1)(=[O:3])[NH2:2]

참가 물질

4

반응물 2

HCID 13461-(2-Methoxyphenyl)piperazineHCID 137294032-Carbamoyl-7-(2,3-epoxypropoxy)benzofuran

생성물 1

HCID 13729383HCID 13729383, 화합물

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

There was suspended 1.2 g (0.005 mole) of 2-carbamoyl-7-(2,3-epoxypropoxy)benzofuran in 15 ml of ethanol, and thereto 1.1 g (0.0055 mole) of 1-(2-methoxyphenyl)piperazine was added. Thereafter, the mixture was refluxed with heating for 2 hours. After completion of the reaction, the solvent was distilled away from the reaction mixture under reduced pressure, and then the resultant residue was crystallized from chloroform and petroleum ether.

후처리

  1. temperatureThereafter, the mixture was refluxed
  2. temperaturewith heating for 2 hours
  3. customAfter completion of the reaction
  4. distillationthe solvent was distilled away from the reaction mixture under reduced pressure
  5. customthe resultant residue was crystallized from chloroform and petroleum ether

출처 및 근거

ORD 기록
ord-b04fffa17ff647cf8475d77b2c6e1a69
출처 데이터셋
uspto-grants-1987_03
특허 번호
US04652566

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