Acrylic Acid → HCID 59737294, 화합물

반응식

Br[C:2]1[CH:3]=[CH:4][C:5]([N:8]2[CH2:13][CH2:12][O:11][CH2:10][CH2:9]2)=[N:6][CH:7]=1.[C:14]([O:18]C(C)(C)C)(=[O:17])[CH:15]=[CH2:16].C(O)(=O)C=C>>[O:11]1[CH2:12][CH2:13][N:8]([C:5]2[N:6]=[CH:7][C:2](/[CH:16]=[CH:15]/[C:14]([OH:18])=[O:17])=[CH:3][CH:4]=2)[CH2:9][CH2:10]1

참가 물질

반응물 3

HCID 6581Acrylic Acid

HCID 15458tert-Butyl acrylate

HCID 109667244-(5-bromopyridin-2-yl)morpholine

생성물 1

HCID 59737294HCID 59737294, 화합물수율 41%

실험 절차

Following the same procedure as described in Example 2, step 2 (scheme 2), but substituting compound 37 for compound 163, and compound 38 for acrylic acid, title compound 164 was obtained (41% yield).

출처 및 근거

ORD 기록: ord-efadfe319a6c4caf97cbac0d1921608f
출처 데이터셋: uspto-grants-2013_12
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08598168B2

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