Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Magnesium peroxide (Mg(O2)) → 4-Methyl-1-phenylisoquinoline
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Magnesium peroxide (Mg(O2)) | HCID 61745 | — |
| 반응물 | 4-Methyl-1-phenyl-3,4-dihydroisoquinoline | HCID 13143580 | — |
| 용매 | Benzene | HCID 241 | — |
| 생성물 | 4-Methyl-1-phenylisoquinoline | HCID 12843495 | 42.5% |
반응 단계
To a suspension of activated magnesium dioxide (270 g, 0.132 mol) in 550 mL of benzene was added 1-phenyl-4-methyl-3,4-dihydroisoquinoline (29.0 g, 0.131 mol) with stirring. The reaction mixture was heated at reflux for 16 hours. The magnesium dioxide was removed by vacuum filtration and washed with methylene chloride. Evaporation of the solvent yielded 12.2 g (42%) of pure yellow crystals of 1-phenyl-4-methylisoquinoline.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08603645B2 |
| 출처 데이터셋 | uspto-grants-2013_12 |
| ORD ID | ord-713ee148d584444f812fc7d9b29f8c64 |
| 출처 메모 | uspto-grants-2013_12 |