Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
(2S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-hydroxyphenyl)propanoic acid → Tyrosine Valine diaminoethane propionyl-maleimide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | (2S)-2-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3-(4-hydroxyphenyl)propanoic acid | HCID 6957986 | — |
| 반응물 | Asparagine Valine diaminoethane propionyl-maleimide | HCID 131731084 | — |
| 생성물 | Tyrosine Valine diaminoethane propionyl-maleimide | HCID 131731083 | — |
반응 단계
AF-Tyrosine-Valine-diaminoethane-propionyl-maleimide (5d) was prepared in the same manner as 5c, using Fmoc-Tyr for AA1. Yield: 36 mg (68%) of white solid. RP-HPLC analysis: >95% at 7.8 min; ESMS m/z=1201.67 (M+H)+.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08609105B2 |
| 출처 데이터셋 | uspto-grants-2013_12 |
| ORD ID | ord-f08853bc42d44319ad12d365d6998f20 |
| 출처 메모 | uspto-grants-2013_12 |