Bromomethylcyclopropane → tert-Butyl 4-{[6-bromo-2-(cyclopropylmethyl)-1-oxo-1,2-dihydroisoquinolin-4-yl]sulfanyl}piperidine-1-carboxylate

반응식

[Br:1][c:2]1[cH:3][c:4]2[c:5]([S:13][CH:14]3[CH2:15][CH2:16][N:17]([C:20](=[O:21])[O:22][C:23]([CH3:24])([CH3:25])[CH3:26])[CH2:18][CH2:19]3)[cH:6][nH:7][c:8](=[O:12])[c:9]2[cH:10][cH:11]1.[CH:27]1([CH2:30][Br:31])[CH2:28][CH2:29]1>>[Br:1][c:2]1[cH:3][c:4]2[c:5]([S:13][CH:14]3[CH2:15][CH2:16][N:17]([C:20](=[O:21])[O:22][C:23]([CH3:24])([CH3:25])[CH3:26])[CH2:18][CH2:19]3)[cH:6][n:7]([CH2:30][CH:27]3[CH2:28][CH2:29]3)[c:8](=[O:12])[c:9]2[cH:10][cH:11]1

참가 물질

반응물 2

HCID 81503Bromomethylcyclopropane

HCID 67130258tert-Butyl 4-[(6-bromo-1-oxo-1,2-dihydroisoquinolin-4-yl)sulfanyl]piperidine-1-carboxylate

생성물 1

HCID 86640974tert-Butyl 4-{[6-bromo-2-(cyclopropylmethyl)-1-oxo-1,2-dihydroisoquinolin-4-yl]sulfanyl}piperidine-1-carboxylate

출처 및 근거

ORD 기록: ord-5b2d236ecbed4d6891118fda7d6a39e0
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (6/10)
DOI: 10.1039/C8SC04228D

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