Cyclohexanone, 3,3-dimethyl- → 3,3-Dimethylcyclohexanone oxime

HRID 1913532노트

반응식

HRID 1913532 반응식
Cl.[NH2:2][OH:3].C([O-])(=O)C.[Na+].[CH3:9][C:10]1([CH3:17])[CH2:15][CH2:14][CH2:13][C:12](=O)[CH2:11]1>O.CO>[CH3:9][C:10]1([CH3:17])[CH2:15][CH2:14][CH2:13][C:12](=[N:2][OH:3])[CH2:11]1

참가 물질

6

반응물 3

HCID 76322Cyclohexanone, 3,3-dimethyl-HCID 443297Hydroxyamine hydrochlorideHCID 517045Sodium Acetate

생성물 1

HCID 594582653,3-Dimethylcyclohexanone oxime

시약·촉매·용매 2

HCID 887Methanol용매HCID 962Water용매

실험 절차

Hydroxylamine hydrochloride (8.76 g) was dissolved in water (100 mL). To the solution, a solution of sodium acetate (17.8 g) and 3,3-dimethylcyclohexanone (4.55 g) in methanol (20 mL) was added at room temperature, and the mixture was heated to reflux for 1.5 hours. Organic matter was extracted with ethyl acetate and dried over anhydrous sodium sulfate, and the solvent was then distilled off under reduced pressure to obtain a crude product of 3,3-dimethylcyclohexanone oxime.

후처리

  1. temperaturethe mixture was heated
  2. temperatureto reflux for 1.5 hours
  3. extractionOrganic matter was extracted with ethyl acetate
  4. dry with materialdried over anhydrous sodium sulfate
  5. distillationthe solvent was then distilled off under reduced pressure

출처 및 근거

ORD 기록
ord-b8844983d42e4f96a1cab0df3d3e73db
출처 데이터셋
uspto-grants-2013_12
특허 번호
US08609710B2

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