Trimethylsilylacetylene → 2-Pyrrolidin-1-ylmethyl-5-trimethylsilanylethynyl-benzoxazole

HRID 1916763노트

반응식

HRID 1916763 반응식
I[C:2]1[CH:3]=[CH:4][C:5]2[O:9][C:8]([CH2:10][N:11]3[CH2:15][CH2:14][CH2:13][CH2:12]3)=[N:7][C:6]=2[CH:16]=1.[C:17]([Si:19]([CH3:22])([CH3:21])[CH3:20])#[CH:18]>>[N:11]1([CH2:10][C:8]2[O:9][C:5]3[CH:4]=[CH:3][C:2]([C:18]#[C:17][Si:19]([CH3:22])([CH3:21])[CH3:20])=[CH:16][C:6]=3[N:7]=2)[CH2:15][CH2:14][CH2:13][CH2:12]1

참가 물질

3

반응물 2

HCID 66111TrimethylsilylacetyleneHCID 690723805-Iodo-2-pyrrolidin-1-ylmethyl-benzoxazole

생성물 1

HCID 673635142-Pyrrolidin-1-ylmethyl-5-trimethylsilanylethynyl-benzoxazole

실험 절차

Prepared analogously to Example 18b from 5-iodo-2-pyrrolidin-1-ylmethyl-benzoxazole and ethynyl-trimethyl-silane.

출처 및 근거

ORD 기록
ord-2156166ebf684349a4a09b4fefef3108
출처 데이터셋
uspto-grants-2013_12
특허 번호
US08618132B2

반응 노트

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