Acetic Anhydride → HCID 20544504, 화합물

HRID 1919575노트

반응식

HRID 1919575 반응식
[NH2:1][C:2]1[S:3][C:4]([C:7]#[N:8])=[CH:5][N:6]=1.[C:9](OC(=O)C)(=[O:11])[CH3:10]>C(O)(=O)C>[C:9]([NH:1][C:2]1[S:3][C:4]([C:7]#[N:8])=[CH:5][N:6]=1)(=[O:11])[CH3:10]

참가 물질

4

반응물 2

HCID 7918Acetic AnhydrideHCID 100575072-Aminothiazole-5-carbonitrile

생성물 1

HCID 20544504HCID 20544504, 화합물수율 80%

시약·촉매·용매 1

HCID 176Acetic Acid용매

실험 절차

2.14 g 2-Amino-5-cyanothiazole was dissolved in 10 ml acetic acid, and 1.8 ml acetic anhydride was added to carry out reaction at 100° C. for 30 min. The reaction product was cooled down, and filtered to obtain 2.5 g of a clay-solid having metallic luster (yield 80%), 1H NMR (DMSO-d6) 2.22 (3H, s), 8.36 (1H, s), 12.95 (1H, s).

후처리

  1. customreaction at 100° C. for 30 min
  2. temperatureThe reaction product was cooled down
  3. filtrationfiltered

출처 및 근거

ORD 기록
ord-47e75d2f864c491e925dee59704ce60e
출처 데이터셋
uspto-grants-2012_05
특허 번호
US08168642B2

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