Pyrrolidine → 2-(5-Fluoro-2-methyl-3-(2-(pyrrolidin-1-ylsulfonyl)benzyl)-1H-indol-1-yl)acetic Acid
반응식
N1CCCC1.[F:6][C:7]1[CH:8]=[C:9]2[C:13](=[CH:14][CH:15]=1)[N:12]([CH2:16][C:17]([OH:19])=[O:18])[C:11]([CH3:20])=[C:10]2[CH2:21][C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][C:23]=1[S:28]([N:31]1[CH2:36]C[CH2:34][CH2:33][CH2:32]1)(=[O:30])=[O:29]>>[F:6][C:7]1[CH:8]=[C:9]2[C:13](=[CH:14][CH:15]=1)[N:12]([CH2:16][C:17]([OH:19])=[O:18])[C:11]([CH3:20])=[C:10]2[CH2:21][C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][C:23]=1[S:28]([N:31]1[CH2:36][CH2:34][CH2:33][CH2:32]1)(=[O:30])=[O:29]참가 물질
3
실험 절차
Pyrrolidine was used as starting material in Procedure Q, otherwise this compound was prepared in a similar manner to Compound 2, using Procedures N, P, Q & L.
출처 및 근거
- ORD 기록
- ord-76ca00852dd24e52a508e54a9ecfd4fd
- 출처 데이터셋
- uspto-grants-2012_05