Methyl bromoacetate → [8-Chloro-4-methyl-2-oxo-3-(4-pyrazol-1-ylbenzyl)-1,2-dihydroquinolin-5-yloxy]acetic acid methyl ester
반응식
[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([OH:26])=[C:6]2[C:11]=1[NH:10][C:9](=[O:12])[C:8]([CH2:13][C:14]1[CH:19]=[CH:18][C:17]([N:20]3[CH:24]=[CH:23][CH:22]=[N:21]3)=[CH:16][CH:15]=1)=[C:7]2[CH3:25].[CH3:27][O:28][C:29](=[O:32])[CH2:30]Br>>[CH3:27][O:28][C:29](=[O:32])[CH2:30][O:26][C:5]1[CH:4]=[CH:3][C:2]([Cl:1])=[C:11]2[C:6]=1[C:7]([CH3:25])=[C:8]([CH2:13][C:14]1[CH:19]=[CH:18][C:17]([N:20]3[CH:24]=[CH:23][CH:22]=[N:21]3)=[CH:16][CH:15]=1)[C:9](=[O:12])[NH:10]2참가 물질
3
실험 절차
The title compound was prepared by the method of Preparation 7a using 8-chloro-5-hydroxy-4-methyl-3-(4-pyrazol-1-ylbenzyl)-1H-quinolin-2-one and bromoacetic acid methyl ester.
출처 및 근거
- ORD 기록
- ord-7b436f4bbfdf46738603652d54e77fbd
- 출처 데이터셋
- uspto-grants-2012_05