Phosphorus oxychloride → HCID 57468659, 화합물

반응식

[Cl:1][C:2]1[CH:3]=[C:4]([C:9]2[CH:14]=[C:13]([CH3:15])[NH:12][C:11](=O)[N:10]=2)[CH:5]=[CH:6][C:7]=1[Cl:8].O=P(Cl)(Cl)[Cl:19]>>[Cl:19][C:11]1[N:10]=[C:9]([C:4]2[CH:5]=[CH:6][C:7]([Cl:8])=[C:2]([Cl:1])[CH:3]=2)[CH:14]=[C:13]([CH3:15])[N:12]=1

참가 물질

반응물 2

HCID 24813Phosphorus oxychloride

HCID 574686604-(3,4-Dichloro-phenyl)-6-methyl-1h-pyrimidin-2-one

생성물 1

HCID 57468659HCID 57468659, 화합물

실험 절차

The title compound was prepared from 4-(3,4-dichloro-phenyl)-6-methyl-1H-pyrimidin-2-one (2.51 g, 9.84 mmol) and phosphoroxychloride (35 mL) according to the general procedure I. Obtained as a brown solid (1.55 g, 58%). MS (EI) 272.1 [(M)+]; mp 123° C. (dec.).

출처 및 근거

ORD 기록: ord-ded1c3acfde146d289b7736d47c67c7f
출처 데이터셋: uspto-grants-2012_05
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08183262B2

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