Phosphorus oxychloride → HCID 57468665, 화합물

HRID 1927843노트

반응식

HRID 1927843 반응식
[Cl:1][C:2]1[CH:3]=[C:4]([C:8]2[CH:13]=[C:12]([C:14]([F:17])([F:16])[F:15])[NH:11][C:10](=O)[N:9]=2)[CH:5]=[CH:6][CH:7]=1.O=P(Cl)(Cl)[Cl:21]>>[Cl:21][C:10]1[N:9]=[C:8]([C:4]2[CH:5]=[CH:6][CH:7]=[C:2]([Cl:1])[CH:3]=2)[CH:13]=[C:12]([C:14]([F:17])([F:16])[F:15])[N:11]=1

참가 물질

3

반응물 2

HCID 24813Phosphorus oxychlorideHCID 574686664-(3-Chloro-phenyl)-6-trifluoromethyl-1h-pyrimidin-2-one

생성물 1

HCID 57468665HCID 57468665, 화합물

실험 절차

The title compound was prepared from 4-(3-chloro-phenyl)-6-trifluoromethyl-1H-pyrimidin-2-one (2.44 g, 8.88 mmol) and phosphoroxychloride (25 mL) according to the general procedure I. Obtained as a white solid (1.62 g, 62%). MS (EI) 292.0 [(M)+]; mp 89.5° C.

출처 및 근거

ORD 기록
ord-f5bd7ef417704dd0bc8a09cc0d12f7a5
출처 데이터셋
uspto-grants-2012_05
특허 번호
US08183262B2

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