1-Methylpiperazine → HCID 44217147, 화합물

반응식

Br[C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[N:8]=[C:7]([NH:12][C@H:13]1[C:21]3[C:16](=[CH:17][CH:18]=[CH:19][CH:20]=3)[CH2:15][CH2:14]1)[CH:6]=[CH:5]2.[CH3:22][N:23]1[CH2:28][CH2:27][NH:26][CH2:25][CH2:24]1>>[C@H:13]1([NH:12][C:7]2[CH:6]=[CH:5][C:4]3[C:9](=[CH:10][CH:11]=[C:2]([N:26]4[CH2:27][CH2:28][N:23]([CH3:22])[CH2:24][CH2:25]4)[CH:3]=3)[N:8]=2)[C:21]2[C:16](=[CH:17][CH:18]=[CH:19][CH:20]=2)[CH2:15][CH2:14]1

참가 물질

반응물 2

HCID 531671-Methylpiperazine

HCID 57860971HCID 57860971, 화합물

생성물 1

HCID 44217147HCID 44217147, 화합물

실험 절차

The title compound, brown oil, MS (ISP): m/e=359.3 (M+H+), was prepared in accordance with the general method of example 163, step B from (6-bromo-quinolin-2-yl)-(R)-indan-1-yl-amine (see example 163, step A) and commercially available 1-methyl-piperazine.

출처 및 근거

ORD 기록: ord-b10173ed970240b89ac29b0e78147e86
출처 데이터셋: uspto-grants-2012_05
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08183380B2

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