Phenylacetyl chloride → 3-(2-phenylacetyl)dihydro-2H-pyran-4(3H)-one

HRID 1930603노트

반응식

[O:1]1[CH2:6][CH2:5][C:4](=[O:7])[CH2:3][CH2:2]1.[C:8]1([CH2:14][C:15](Cl)=[O:16])[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1>>[C:8]1([CH2:14][C:15]([CH:3]2[C:4](=[O:7])[CH2:5][CH2:6][O:1][CH2:2]2)=[O:16])[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1

참가 물질

반응물 2

HCID 7679Phenylacetyl chloride

HCID 121599Tetrahydro-4H-pyran-4-one

생성물 1

HCID 593337793-(2-phenylacetyl)dihydro-2H-pyran-4(3H)-one수율 61%

실험 절차

3-(2-Phenylacetyl)dihydro-2H-pyran-4(3H)-one (0.855 g, 61%) was obtained from tetrahydro-4H-pyran-4-one and phenylacetyl chloride using the general procedure for the preparation of diketones. MS (ES+) m/z 219.1 (M+H)+

출처 및 근거

ORD 기록: ord-f06d91cae20b4e9bb0a9f2f24142abc0
출처 데이터셋: uspto-grants-2012_05
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08188101B2

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