Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1,1'-Carbonyldiimidazole → HCID 59333745, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1,1'-Carbonyldiimidazole | HCID 68263 | — |
| 반응물 | 3-(Oxolan-2-yl)propanoic acid | HCID 263161 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | HCID 59333745 | HCID 59333745 | 100.1% |
반응 단계
Di-(1H-imidazol-1-yl)methanone (0.554 g, 3.42 mmol) was added in small portions to a stirred solution of 3-(tetrahydrofuran-2-yl)propanoic acid (0.469 g, 3.25 mmol) in dichloromethane (3 mL) at room temperature under argon. The reaction mixture is stirred at room temperature for 2 hours. The mixture was washed twice with water, dried over MgSO4 and concentrated resulting a quantitative yield of 1-(1H-imidazol-1-yl)-3-(tetrahydrofuran-2-yl)propan-1-one (632 mg, 100%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08188101B2 |
| 출처 데이터셋 | uspto-grants-2012_05 |
| ORD ID | ord-2cb04fbc9ad746529d70a437f4cdea17 |
| 출처 메모 | uspto-grants-2012_05 |