Hydrochloric Acid → 5-(Tetrahydro-pyran-4-yl)-2,3-dihydro-1H-isoindole hydrochloride

반응식

C(OC([N:8]1[CH2:16][C:15]2[C:10](=[CH:11][CH:12]=[C:13]([CH:17]3[CH2:22][CH2:21][O:20][CH2:19][CH2:18]3)[CH:14]=2)[CH2:9]1)=O)(C)(C)C.[ClH:23]>>[ClH:23].[O:20]1[CH2:21][CH2:22][CH:17]([C:13]2[CH:14]=[C:15]3[C:10](=[CH:11][CH:12]=2)[CH2:9][NH:8][CH2:16]3)[CH2:18][CH2:19]1

참가 물질

반응물 2

HCID 313Hydrochloric Acid

HCID 57753401HCID 57753401, 화합물

생성물 1

HCID 688258015-(Tetrahydro-pyran-4-yl)-2,3-dihydro-1H-isoindole hydrochloride

실험 절차

Prepared in analogy to Example A3(e) from 5-(tetrahydro-pyran-4-yl)-1,3-dihydro-isoindole-2-carboxylic acid tert-butyl ester and hydrochloric acid. White solid. MS (m/e): 204.3 ([M+H]+, 100%).

출처 및 근거

ORD 기록: ord-d3b35fee3b934af0911f9b65de581f0d
출처 데이터셋: uspto-grants-2012_05
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08188139B2

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