Iodoethane → Methyl 3-ethoxy-4-methoxybenzoate
반응식
[OH:1][C:2]1[CH:3]=[C:4]([CH:9]=[CH:10][C:11]=1[O:12][CH3:13])[C:5]([O:7][CH3:8])=[O:6].C(=O)([O-])[O-].[K+].[K+].[CH2:20](I)[CH3:21]>CN(C)C=O>[CH2:20]([O:1][C:2]1[CH:3]=[C:4]([CH:9]=[CH:10][C:11]=1[O:12][CH3:13])[C:5]([O:7][CH3:8])=[O:6])[CH3:21]참가 물질
5
실험 절차
To a mixture of methyl 3-hydroxy-4-methoxybenzoate (4.00 g) and potassium carbonate (4.55 g) in dimethylformamide (20 mL) was added ethyl iodide (2.63 mL) under water-cooling and the mixture was stirred for 2 hours at ambient temperature. The mixture was partitioned between water and ethyl acetate. The separated organic layer was washed with water and brine, dried over magnesium sulfate and evaporated in vacuo to give methyl 3-ethoxy-4-methoxybenzoate as pale brown powders (4.55 g).
후처리
- temperaturecooling
- customThe mixture was partitioned between water and ethyl acetate
- washThe separated organic layer was washed with water and brine
- dry with materialdried over magnesium sulfate
- customevaporated in vacuo
출처 및 근거
- ORD 기록
- ord-74d2c9a455b34eb781fbbe8965161b48
- 출처 데이터셋
- uspto-grants-2002_05
- 특허 번호
- US06384080B1
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