3-(4-Methoxyphenyl)-2-phenylprop-2-enoic acid → 3-(4-Methoxyphenyl)-2-phenylpropionic acid

HRID 1935734

반응식

HRID 1935734 반응식
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([CH:9]=[C:10]([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[C:11]([OH:13])=[O:12])=[CH:5][CH:4]=1>[Pd].C(O)(=O)C>[CH3:1][O:2][C:3]1[CH:4]=[CH:5][C:6]([CH2:9][CH:10]([C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[C:11]([OH:13])=[O:12])=[CH:7][CH:8]=1

참가 물질

4

반응물 1

HCID 2366983-(4-Methoxyphenyl)-2-phenylprop-2-enoic acid

생성물 1

HCID 977393-(4-Methoxyphenyl)-2-phenylpropionic acid

시약·촉매·용매 2

HCID 23938Palladium촉매HCID 176Acetic Acid용매

실험 절차

Palladium on activated carbon (10% wt., 2.77 g) was added to a solution of 3-(4-methoxyphenyl)-2-phenylacrylic acid (27.7 g, 0.11 mol) in acetic acid (1000 ml). The mixture was hydrogenated at ambient temperature. The mixture was filtered through Celite, and the solvent was evaporated. The product was recrystallized from a small amount of ethyl acetate. Melting point 220-221° C.

후처리

  1. customwas hydrogenated at ambient temperature
  2. filtrationThe mixture was filtered through Celite
  3. customthe solvent was evaporated
  4. customThe product was recrystallized from a small amount of ethyl acetate

출처 및 근거

ORD 기록
ord-1882dce487974d0793678a129d3179de
출처 데이터셋
uspto-grants-2002_05
특허 번호
US06388090B2

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