Triethylamine → HCID 22462540, 화합물

HRID 1936722

반응식

HRID 1936722 반응식
[N:1]1[CH:6]=[CH:5][C:4]([C:7]2[C:16]3[C:11](=[CH:12][CH:13]=[CH:14][CH:15]=3)[C:10]([NH2:17])=[CH:9][CH:8]=2)=[CH:3][CH:2]=1.[CH3:18][N:19]1[CH2:24][CH2:23][CH:22]([C:25]2[C:33]3[CH:32]=[C:31]4[NH:34][CH2:35][CH2:36][C:30]4=[CH:29][C:28]=3[NH:27][CH:26]=2)[CH2:21][CH2:20]1.ClC(Cl)(O[C:41](=[O:47])OC(Cl)(Cl)Cl)Cl.C([N:51](CC)CC)C>>[CH3:18][N:19]1[CH2:24][CH2:23][CH:22]([C:25]2[C:33]3[CH:32]=[C:31]4[N:34]([NH:51][C:41]([NH:17][C:10]5[C:11]6[C:16](=[CH:15][CH:14]=[CH:13][CH:12]=6)[C:7]([C:4]6[CH:3]=[CH:2][N:1]=[CH:6][CH:5]=6)=[CH:8][CH:9]=5)=[O:47])[CH2:35][CH2:36][C:30]4=[CH:29][C:28]=3[NH:27][CH:26]=2)[CH2:21][CH2:20]1

참가 물질

5

반응물 4

HCID 8471TriethylamineHCID 94429TriphosgeneHCID 108570124-(Pyridin-4-yl)naphth-1-ylamineHCID 17898952HCID 17898952, 화합물

생성물 1

HCID 22462540HCID 22462540, 화합물

실험 절차

The title compound was prepared in a similar manner to Example 1 from 4-(pyridin-4-yl)naphth-1-ylamine (D3, 0.16 g, 0.7 mmole), 7-(1-methylpiperidin-4-yl)-1,2,3,5-tetrahydropyrrolo[2,3-f]indole (D6, 0.15 g, 0.6 mmole), triphosgene (0.08 g, 0.28 mmole) and triethylamine (0.25 ml). This was obtained as a cream powder (0.11 g).

출처 및 근거

ORD 기록
ord-ae2ba6d2679848f7bb9b2dd18a01a4d6
출처 데이터셋
uspto-grants-2002_05
특허 번호
US06391891B1

연결된 노트

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