Phosphorus sulfide (P2S5) → Tetradecanethioamide

HRID 1938745

반응식

HRID 1938745 반응식
P12(SP3(SP(SP(S3)(S1)=S)(=S)S2)=S)=[S:2].[C:15]([NH2:30])(=O)[CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH3:28]>C1COCC1>[C:15](=[S:2])([NH2:30])[CH2:16][CH2:17][CH2:18][CH2:19][CH2:20][CH2:21][CH2:22][CH2:23][CH2:24][CH2:25][CH2:26][CH2:27][CH3:28]

참가 물질

4

반응물 2

HCID 14817Phosphorus sulfide (P2S5)HCID 69492Tetradecanamide

생성물 1

HCID 21469509Tetradecanethioamide수율 105.6%

시약·촉매·용매 1

HCID 8028Tetrahydrofuran용매

실험 절차

Phosphorus pentasulfide (9.8 g, 0.044 mol) was added to a mixture of tetradecanamide (8.6 g, 0.04 mol) in dry THF (250 mL) and the mixture refluxed overnight, concentrated in vacuo, and heated with methanol (200 mL), filtered, and the filtrate concentrated in vacuo to yield a pale yellow solid (10.28 g, 99%) used without further purification.

후처리

  1. temperaturethe mixture refluxed overnight
  2. concentrationconcentrated in vacuo
  3. temperatureheated with methanol (200 mL)
  4. filtrationfiltered
  5. concentrationthe filtrate concentrated in vacuo

출처 및 근거

ORD 기록
ord-9c1bba6281194e248ea2e149a2aa8903
출처 데이터셋
uspto-grants-1997_12
특허 번호
US05693657

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