Benzoyl chloride → Benzamide, N-(4-hydroxybutyl)-
반응식
[C:1](Cl)(=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[NH2:10][CH2:11][CH2:12][CH2:13][CH2:14][OH:15].C(N(CC)CC)C.C(=O)([O-])[O-].[Na+].[Na+]>ClCCl>[OH:15][CH2:14][CH2:13][CH2:12][CH2:11][NH:10][C:1](=[O:8])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1참가 물질
6
실험 절차
A solution of 1.16 mL (10 mmol) of benzoylchloride in 10 mL dichloromethane is added to 0.93 mL (10 mmol) of 4-amino-butan-1-ol and 4.2 mL (30 mmol) of triethylamine dissolved in 50 mL of dichloromethane. The mixture is stirred overnight. 50 mL of saturated sodium carbonate solution is added. The organic phase is separated, dried with sodium sulfate and the solvent evaporated.
후처리
- customThe organic phase is separated
- dry with materialdried with sodium sulfate
- customthe solvent evaporated
출처 및 근거
- ORD 기록
- ord-d7cddf9df1b04cc0ae01a38c48c794fa
- 출처 데이터셋
- uspto-grants-2013_03
- 특허 번호
- US08389555B2
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