Diisopropylethylamine → 4-{2-[2-(Benzyloxycarbonyl-methyl-amino)-propionylamino]-3-tert-butoxy-butyryl}-3-(6-fluoro-1H-indol-3-yl)-hexahydro-pyrrolo[3,2-b]pyrrole-1-carboxylic acid benzyl ester

반응식

[C:1]([N:11]([CH3:17])[C@H:12]([C:14]([OH:16])=O)[CH3:13])([O:3][CH2:4][C:5]1[CH:10]=[CH:9][CH:8]=[CH:7][CH:6]=1)=[O:2].CN(C(ON1N=NC2C=CC=NC1=2)=[N+](C)C)C.F[P-](F)(F)(F)(F)F.CCN(C(C)C)C(C)C.[CH2:51]([O:58][C:59]([N:61]1[CH2:65][CH:64]([C:66]2[C:74]3[C:69](=[CH:70][C:71]([F:75])=[CH:72][CH:73]=3)[NH:68][CH:67]=2)[CH:63]2[N:76]([C:79](=[O:89])[CH:80]([NH2:88])[CH:81]([O:83][C:84]([CH3:87])([CH3:86])[CH3:85])[CH3:82])[CH2:77][CH2:78][CH:62]12)=[O:60])[C:52]1[CH:57]=[CH:56][CH:55]=[CH:54][CH:53]=1>CN1C(=O)CCC1.CCOC(C)=O>[CH2:51]([O:58][C:59]([N:61]1[CH2:65][CH:64]([C:66]2[C:74]3[C:69](=[CH:70][C:71]([F:75])=[CH:72][CH:73]=3)[NH:68][CH:67]=2)[CH:63]2[N:76]([C:79](=[O:89])[CH:80]([NH:88][C:14](=[O:16])[CH:12]([N:11]([C:1]([O:3][CH2:4][C:5]3[CH:6]=[CH:7][CH:8]=[CH:9][CH:10]=3)=[O:2])[CH3:17])[CH3:13])[CH:81]([O:83][C:84]([CH3:86])([CH3:85])[CH3:87])[CH3:82])[CH2:77][CH2:78][CH:62]12)=[O:60])[C:52]1[CH:53]=[CH:54][CH:55]=[CH:56][CH:57]=1