L-Lysine → 7-Amino-2-oxoheptanoic acid

HRID 1950689

반응식

HRID 1950689 반응식
[NH2:1][C@H:2](C(O)=O)CCCCN.N[CH2:12][CH2:13][CH2:14][CH2:15][C:16](=[O:20])[C:17]([OH:19])=[O:18]>>[NH2:1][CH2:2][CH2:12][CH2:13][CH2:14][CH2:15][C:16](=[O:20])[C:17]([OH:19])=[O:18]

참가 물질

3

반응물 2

HCID 5962L-LysineHCID 4399546-Amino-2-oxohexanoic acid2회

생성물 1

HCID 574852297-Amino-2-oxoheptanoic acid

실험 절차

In an alternative embodiment, lysine is first converted to 6-amino-2-oxohexanoic acid by an aminotransferase enzyme (EC 2.6.1.x) or a dehydrogenase (EC 1.4.1.x or EC 1.4.3.x). Preferred enzymes are listed in Table 7 and may be engineered to catalyze the desired substrate to product reaction. In a subsequent step, 6-amino-2-oxohexanoic acid is subjected to a carbon elongation enzymatic step to produce 7-amino-2-oxoheptanoic acid.

후처리

  1. customto product reaction

출처 및 근거

ORD 기록
ord-b8f58644838640a4b61f784a02a4b55e
출처 데이터셋
uspto-grants-2013_03
특허 번호
US08404465B2

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