Hydrochloric Acid → 4-(3-Methyl-1,2,4-oxadiazol-5-ylmethyl)benzenemethanamine-hydrochloride

HRID 1953024노트

반응식

CC(C)(OC([NH:7][CH2:8][C:9]1[CH:14]=[CH:13][C:12]([CH2:15][C:16]2[O:20][N:19]=[C:18]([CH3:21])[N:17]=2)=[CH:11][CH:10]=1)=O)C.[ClH:23]>>[ClH:23].[CH3:21][C:18]1[N:17]=[C:16]([CH2:15][C:12]2[CH:13]=[CH:14][C:9]([CH2:8][NH2:7])=[CH:10][CH:11]=2)[O:20][N:19]=1

참가 물질

반응물 2

HCID 313Hydrochloric Acid

HCID 23301891HCID 23301891, 화합물

생성물 1

HCID 233017734-(3-Methyl-1,2,4-oxadiazol-5-ylmethyl)benzenemethanamine-hydrochloride수율 56%

실험 절차

Prepared analogously to Example 65i) by treating 5-[[4-[[[(1,1-dimethylethoxy)carbonyl]amino]methyl]phenyl]methyl]-3-methyl-1,2,4-oxadiazole with methanolic hydrogen chloride solution in a yield of 56% of theory.

후처리

customPrepared analogously to Example 65i)

출처 및 근거

ORD 기록: ord-b28baca624bc46269f97660c55f636c1
출처 데이터셋: uspto-grants-2000_09
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US06114390

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