Benzoyl Peroxide → 3-(Bromomethyl)biphenyl

HRID 1957003

반응식

HRID 1957003 반응식
[CH3:1][C:2]1[CH:3]=[C:4]([C:8]2[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=2)[CH:5]=[CH:6][CH:7]=1.[Br:14]N1C(=O)CCC1=O.C(OOC(=O)C1C=CC=CC=1)(=O)C1C=CC=CC=1>C(Cl)(Cl)(Cl)Cl>[C:8]1([C:4]2[CH:3]=[C:2]([CH:7]=[CH:6][CH:5]=2)[CH2:1][Br:14])[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1

참가 물질

5

반응물 3

HCID 7187Benzoyl PeroxideHCID 125643-MethylbiphenylHCID 67184N-bromobutanimide

생성물 1

HCID 38644053-(Bromomethyl)biphenyl

시약·촉매·용매 1

HCID 5943Carbon Tetrachloride용매

실험 절차

A mixture of 3-methylbiphenyl (5.23 g, 31.1 mmol), N-bromosuccinimide (5.56 g, 31.2 mmol), benzoyl peroxide (135 mg, 0.56 mmol), and carbon tetrachloride (150 ml) is refluxed for 17 h. The mixture is concentrated in vacuo and the residue is purified by flash column chromatography (hexane) to give 3-phenylbenzyl bromide.

후처리

  1. temperatureis refluxed for 17 h
  2. concentrationThe mixture is concentrated in vacuo
  3. customthe residue is purified by flash column chromatography (hexane)

출처 및 근거

ORD 기록
ord-e6b235cc9e144fd1a618c058180307e5
출처 데이터셋
uspto-grants-1998_07
특허 번호
US05780498

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