Benzoyl Peroxide → 3-(4-(Bromomethyl)phenyl)thiophene

HRID 1957019노트

반응식

HRID 1957019 반응식
[S:1]1[CH:5]=[CH:4][C:3]([C:6]2[CH:11]=[CH:10][C:9]([CH3:12])=[CH:8][CH:7]=2)=[CH:2]1.[Br:13]N1C(=O)CCC1=O.C(OOC(=O)C1C=CC=CC=1)(=O)C1C=CC=CC=1>C(Cl)(Cl)(Cl)Cl>[S:1]1[CH:5]=[CH:4][C:3]([C:6]2[CH:11]=[CH:10][C:9]([CH2:12][Br:13])=[CH:8][CH:7]=2)=[CH:2]1

참가 물질

5

반응물 3

HCID 7187Benzoyl PeroxideHCID 67184N-bromobutanimideHCID 41303473-(4-Methylphenyl)thiophene

생성물 1

HCID 137735383-(4-(Bromomethyl)phenyl)thiophene

시약·촉매·용매 1

HCID 5943Carbon Tetrachloride용매

실험 절차

To a solution of 4-(3-thienyl)toluene (3.56 g, 20.5 mmol) in carbon tetrachloride (100 ml) is added N-bromosuccinimide (3.64 g, 20.5 mol) and benzoyl peroxide (80 mg, 3.3 mmol). The reaction mixture is heated at reflux for 24 hrs. and concentrated in vacuo. The reaction mixture is recrystallized from ethanol to afford 4-(3-thienyl)benzyl bromide.

후처리

  1. temperatureThe reaction mixture is heated
  2. temperatureat reflux for 24 hrs
  3. concentrationand concentrated in vacuo
  4. customThe reaction mixture is recrystallized from ethanol

출처 및 근거

ORD 기록
ord-ef8bed6f4a65437fb5f42700a13c9323
출처 데이터셋
uspto-grants-1998_07
특허 번호
US05780498

반응 노트

불러오는 중…