Tetrahydrofuran → 5-(4-Methoxy-phenyl)-7-methyl-2-(3-piperidin-1-yl-propoxy)-5,6,7,8-tetrahydro-[1,7]naphthyridine

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[CH2:50]1[O:51][CH2:52][CH2:53][CH2:54]1.[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6]([CH:9]2[c:10]3[cH:11][cH:12][c:13]([OH:20])[n:14][c:15]3[CH2:16][N:17]([CH3:19])[CH2:18]2)[cH:7][cH:8]1.[N:40]1([CH2:46][CH2:47][CH2:48][OH:49])[CH2:41][CH2:42][CH2:43][CH2:44][CH2:45]1.[c:21]1([P:22]([c:23]2[cH:24][cH:25][cH:26][cH:27][cH:28]2)[c:29]2[cH:30][cH:31][cH:32][cH:33][cH:34]2)[cH:35][cH:36][cH:37][cH:38][cH:39]1>>[CH3:1][O:2][c:3]1[cH:4][cH:5][c:6]([CH:9]2[c:10]3[cH:11][cH:12][c:13]([O:20][CH2:48][CH2:47][CH2:46][N:40]4[CH2:41][CH2:42][CH2:43][CH2:44][CH2:45]4)[n:14][c:15]3[CH2:16][N:17]([CH3:19])[CH2:18]2)[cH:7][cH:8]1