Tetrahydrofuran → 2-{[4-(4-Bromophenyl)-1,3-thiazol-2-yl]amino}-4,4,4-trifluorobutan-1-ol

HRID 195902노트

반응식

[Al+3:25].[Br:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[n:9][c:10]([NH:13][CH:14]([C:15](=[O:16])[O:17][CH3:18])[CH2:19][C:20]([F:21])([F:22])[F:23])[s:11][cH:12]2)[cH:6][cH:7]1.[H-:24].[H-:27].[H-:28].[H-:29].[Li+:26].[O:30]1[CH2:31][CH2:32][CH2:33][CH2:34]1>>[Br:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[n:9][c:10]([NH:13][CH:14]([CH2:15][OH:16])[CH2:19][C:20]([F:21])([F:22])[F:23])[s:11][cH:12]2)[cH:6][cH:7]1