Sodium hydride → HCID 23659518, 화합물

HRID 1968400

반응식

HRID 1968400 반응식
[CH3:1][S:2][C:3]1[S:7][N:6]=[C:5]([SH:8])[N:4]=1.[H-].[Na+].Cl[C:12]1[C:13]([C:18]#[N:19])=[N:14][CH:15]=[CH:16][N:17]=1>CN(C=O)C.C1C=CC=CC=1>[CH3:1][S:2][C:3]1[S:7][N:6]=[C:5]([S:8][C:12]2[C:13]([C:18]#[N:19])=[N:14][CH:15]=[CH:16][N:17]=2)[N:4]=1

참가 물질

6

반응물 3

HCID 24758Sodium hydrideHCID 2924653-Chloropyrazine-2-carbonitrileHCID 178503581HCID 178503581, 화합물

생성물 1

HCID 23659518HCID 23659518, 화합물

시약·촉매·용매 2

HCID 241Benzene용매HCID 6228Dimethylformamide용매

실험 절차

The title compound was prepared according to Example 1 by using 5-(methylthio)-1,2,4-thiadiazole-3-thiol (328 mg, 2.00 mmol), NaH (60% dispersion in mineral oil, 88 mg, 2.20 mmol), and 3-chloropyrazine-2-carbonitrile (280 mg, 2.00 mmol) in DMF and benzene (6 ml, 1/1) by stirring at room temperature under nitrogen atmosphere for 2 hr.

출처 및 근거

ORD 기록
ord-8da76539cf98484280bae7dd7741565c
출처 데이터셋
uspto-grants-2013_04
특허 번호
US08426358B2

연결된 노트

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