Benzoyl chloride → (3-{2-[(Benzoyl-ethyl-amino)-methyl]-4-trifluoromethyl-phenoxy}-phenyl)-acetic acid methyl ester

HRID 1969053노트

반응식

HRID 1969053 반응식
[CH3:1][O:2][C:3](=[O:26])[CH2:4][C:5]1[CH:10]=[CH:9][CH:8]=[C:7]([O:11][C:12]2[CH:17]=[CH:16][C:15]([C:18]([F:21])([F:20])[F:19])=[CH:14][C:13]=2[CH2:22][NH:23][CH2:24][CH3:25])[CH:6]=1.[C:27](Cl)(=[O:34])[C:28]1[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=1>>[CH3:1][O:2][C:3](=[O:26])[CH2:4][C:5]1[CH:10]=[CH:9][CH:8]=[C:7]([O:11][C:12]2[CH:17]=[CH:16][C:15]([C:18]([F:20])([F:19])[F:21])=[CH:14][C:13]=2[CH2:22][N:23]([C:27](=[O:34])[C:28]2[CH:33]=[CH:32][CH:31]=[CH:30][CH:29]=2)[CH2:24][CH3:25])[CH:6]=1

참가 물질

3

반응물 2

HCID 7412Benzoyl chlorideHCID 58288538[3-(2-Ethylaminomethyl-4-trifluoromethyl-phenoxy)-phenyl]-acetic acid methyl ester

생성물 1

HCID 58288505(3-{2-[(Benzoyl-ethyl-amino)-methyl]-4-trifluoromethyl-phenoxy}-phenyl)-acetic acid methyl ester

실험 절차

Prepared according to the procedure described in Example 15, Step 7, using the following starting materials: [3-(2-ethylaminomethyl-4-trifluoromethyl-phenoxy)-phenyl]-acetic acid methyl ester and benzoyl chloride.

후처리

  1. customPrepared

출처 및 근거

ORD 기록
ord-a78937dc30fc4030be1e0020e8a2413f
출처 데이터셋
uspto-grants-2013_04
특허 번호
US08426449B2

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