Azobisisobutyronitrile → HCID 178459095, 화합물

HRID 1972299

반응식

HRID 1972299 반응식
CC(N=NC(C#N)(C)C)(C#N)C.C[CH2:14][C:15]([CH2:20][O:21][CH2:22][CH:23]=[CH2:24])(CO)CO.[C:25]([OH:30])(=[S:29])[CH:26]([CH3:28])[OH:27]>CO.C1(C)C=CC=CC=1.CCCCCC>[CH2:20]([O:21][CH2:22][CH:23]=[CH2:24])[CH:15]=[CH2:14].[C:25]([OH:30])(=[S:29])[CH:26]([CH3:28])[OH:27]

참가 물질

7

반응물 3

HCID 6547AzobisisobutyronitrileHCID 12683Trimethylolpropane monoallyl etherHCID 178473673HCID 178473673, 화합물

생성물 1

HCID 178459095HCID 178459095, 화합물

시약·촉매·용매 3

HCID 887Methanol용매HCID 1140Toluene용매HCID 8058Hexane용매

반응 조건

온도
90 °C

실험 절차

AIBN (1.5 g) was dissolved in trimethylolpropane monoallyl ether (497 g, 2.86 mol). This solution was slowly added, under nitrogen with stirring, to thiolactic acid (300 g, 2.83 mol) at such a rate that the temperature of the exothermal reaction was kept at 80° C. When the addition was completed, the temperature was raised to 90° C. and kept at 90° C. for 1 h. The product had 1H-NMR (CDCl3): δ 1.11 (t, 3H, CH3CH2), 1.53 (q, 2H, CH3CH2), 2.00-2.20 (m, 2H, CH2CH2CH2), 2.98-3.06 (m, 2H, 3.65-4.02 (m, 9H); and is soluble in methanol and toluene, not soluble in hexane.

후처리

  1. additionThis solution was slowly added, under nitrogen
  2. customthat the temperature of the exothermal reaction
  3. customwas kept at 80° C
  4. additionWhen the addition

출처 및 근거

ORD 기록
ord-641a1f01701d42dc9ace8d49418ea828
출처 데이터셋
uspto-grants-2013_04
특허 번호
US08431748B2

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