Dimethylamine → HCID 54371367, 화합물

HRID 1973341노트

반응식

HRID 1973341 반응식
[NH2:1][C:2]1[N:3]=[C:4]([C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)[N:5]([CH3:12])[C:6]=1[C:7]([O:9][CH2:10][CH3:11])=[O:8].[N:19]([O-])=O.[Na+].C(=O)([O-])[O-].[Na+].[Na+].[CH3:29][NH:30][CH3:31]>Cl.O>[C:7]([C:6]1[N:5]([CH3:12])[C:4]([C:13]2[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=2)=[N:3][C:2]=1[N:1]=[N:19][N:30]([CH3:31])[CH3:29])([O:9][CH2:10][CH3:11])=[O:8]

참가 물질

7

반응물 4

HCID 674DimethylamineHCID 10340Sodium CarbonateHCID 21491188HCID 21491188, 화합물HCID 23668193Sodium Nitrite

생성물 1

HCID 54371367HCID 54371367, 화합물

시약·촉매·용매 2

HCID 313Hydrochloric Acid용매HCID 962Water용매

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온도
0 °C

실험 절차

4-Amino-5-carbethoxy-1-methyl-2-phenyl imidazole (2.84) [made by the method of Cook et. al, Journal of the Chemical Society, 1950 (2775)] in 5N hydrochloric acid (24.0 ml) was cooled to 0° C and a cold solution of sodium nitrite (0.96 gm) in water (5 ml) added slowly, with stirring, keeping the mixture at 0° C. The resulting solution was added dropwise to a cold (0° C) mixture of sodium carbonate (120 mls of 30%) and dimethylamine (2.5 mls of 25% aqueous solution).

후처리

  1. customat 0° C

출처 및 근거

ORD 기록
ord-385d748a7269403bb7e84df1ae952c1e
출처 데이터셋
uspto-grants-1976_12
특허 번호
US03997518

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