Sodium Hydroxide → (2E)-N-(3,4-Dichlorophenyl)-2H-quinolizin-2-imine

HRID 1973385노트

반응식

HRID 1973385 반응식
[Br-].[Cl:2][C:3]1[CH:4]=[C:5]([CH:17]=[CH:18][C:19]=1[Cl:20])[NH:6][C:7]1[CH:16]=[CH:15][N+:14]2[C:9](=[CH:10][CH:11]=[CH:12][CH:13]=2)[CH:8]=1.[OH-].[Na+]>O>[Cl:2][C:3]1[CH:4]=[C:5]([N:6]=[C:7]2[CH:16]=[CH:15][N:14]3[C:9]([CH:10]=[CH:11][CH:12]=[CH:13]3)=[CH:8]2)[CH:17]=[CH:18][C:19]=1[Cl:20]

참가 물질

4

반응물 2

HCID 14798Sodium HydroxideHCID 38666Nolinium Bromide

생성물 1

HCID 330198(2E)-N-(3,4-Dichlorophenyl)-2H-quinolizin-2-imine

시약·촉매·용매 1

HCID 962Water용매

실험 절차

A solution of 2-(3,4-dichloroanilino)quinolizinium bromide (23 g, 0.062 mole) in water (1 l.) was warmed to 50°. The warm solution was stirred and treated with a 2 N solution of NaOH (400 ml). The solution precipitated a yellow-orange product and the aqueous solution was warmed at 50° for 1 hour. After cooling and filtration the air dried product weighed 18 g (100%).

후처리

  1. customThe solution precipitated a yellow-orange product
  2. temperaturethe aqueous solution was warmed at 50° for 1 hour
  3. temperatureAfter cooling
  4. filtrationfiltration the air dried product

출처 및 근거

ORD 기록
ord-d81eaf1f31c94ff881587183744e14ab
출처 데이터셋
uspto-grants-1976_12
특허 번호
US03997547

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