Potassium → N-[2-(2-methyl-5-nitro-1-imidazolyl)ethyl]-acenaphthene-1,2-dicarboximide

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[CH:1]12[C:15](=[O:16])[NH:14][C:13](=[O:17])[CH:2]1[C:3]1[C:12]3[C:7](=[CH:8][CH:9]=[CH:10][C:11]2=3)[CH:6]=[CH:5][CH:4]=1.[K].S(C1C=CC(C)=CC=1)(O)(=O)=O.O[CH2:31][CH2:32][N:33]1[C:37]([N+:38]([O-:40])=[O:39])=[CH:36][N:35]=[C:34]1[CH3:41]>O>[CH3:41][C:34]1[N:33]([CH2:32][CH2:31][N:14]2[C:13](=[O:17])[CH:2]3[C:3]4[C:12]5[C:7](=[CH:8][CH:9]=[CH:10][C:11]=5[CH:1]3[C:15]2=[O:16])[CH:6]=[CH:5][CH:4]=4)[C:37]([N+:38]([O-:40])=[O:39])=[CH:36][N:35]=1

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실험 절차

Acenaphthene-1,2-dicarboximide is converted to the potassium salt and reacted with 1-(2-hydroxyethyl)-2-methyl-5-nitroimidazole tosylate according to the procedure described in Example 13. The crude reaction mixture is cooled and diluted with water, and then extracted with toluene. The solvent is evaporated from the toluene extract and the residue recrystallized from ethanol to give N-[2-(2-methyl-5-nitro-1-imidazolyl)ethyl]-acenaphthene-1,2-dicarboximide melting at about 183°-185° C.