Potassium thiocyanate → HCID 54155438, 화합물

HRID 1973631노트

반응식

HRID 1973631 반응식
Cl[CH2:2][CH2:3][C:4]([N:6]1[CH2:10][CH2:9][CH2:8][CH2:7]1)=[O:5].[S-:11][C:12]#[N:13].[K+]>C(O)C>[S:11]([CH2:2][CH2:3][C:4]([N:6]1[CH2:10][CH2:9][CH2:8][CH2:7]1)=[O:5])[C:12]#[N:13]

참가 물질

4

반응물 2

HCID 516872Potassium thiocyanateHCID 32712663-Chloro-1-(pyrrolidin-1-yl)propan-1-one

생성물 1

HCID 54155438HCID 54155438, 화합물

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

1-(β-Chloropropionyl) pyrrolidine (16 grams; 0.1 mol), potassium thiocyanate (18 grams; 0.2 mol) and ethanol (100 ml) are charged into a glass reaction flask equipped with a mechanical stirrer and reflux condenser. The reaction mixture is then heated at reflux for a period of about 6 hours. After this time the reaction mixture is cooled and filtered. The filtrate is stripped of solvent and the residue is extracted with benzene. The benzene extract is evaporated under reduced pressure to yield 1-(β-thiocyanopropionyl) pyrrolidine as a residue.

후처리

  1. customequipped with a mechanical stirrer
  2. temperaturereflux condenser
  3. temperatureThe reaction mixture is then heated
  4. temperatureat reflux for a period of about 6 hours
  5. temperatureAfter this time the reaction mixture is cooled
  6. filtrationfiltered
  7. extractionthe residue is extracted with benzene
  8. extractionThe benzene extract
  9. customis evaporated under reduced pressure

출처 및 근거

ORD 기록
ord-7a66f3532b734bfc87c1ddce421c0ab0
출처 데이터셋
uspto-grants-1976_12
특허 번호
US03998808

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