HCID 53847304, 화합물 → HCID 22795184, 화합물
반응식
C[O:2][C:3]1[CH:4]=[C:5]([C@H:9]2[CH2:14][CH2:13][CH2:12][CH2:11][C@H:10]2[N:15]2[CH2:19][CH2:18][CH2:17][CH2:16]2)[CH:6]=[CH:7][CH:8]=1>Br.O>[OH:2][C:3]1[CH:4]=[C:5]([C@H:9]2[CH2:14][CH2:13][CH2:12][CH2:11][C@H:10]2[N:15]2[CH2:19][CH2:18][CH2:17][CH2:16]2)[CH:6]=[CH:7][CH:8]=1참가 물질
4
실험 절차
(1) The above oil (19g) was boiled in 47% hydrobromic acid (60 ml) for six hours. The cooled solution was diluted with water, washed with ether, basified and ether extracted. The dried extract was evaporated. The residue was triturated with petroleum ether (b.p. 40° to 60° C) and crystallised from petroleum ether (b.p. 60° to 80° C)/ ethyl acetate to give cis-2-(3-hydroxyphenyl)-1-pyrrolidinocyclohexane (12g), m.p. 124° to 126° C.
후처리
- washwashed with ether
- extractionether extracted
- extractionThe dried extract
- customwas evaporated
- customThe residue was triturated with petroleum ether (b.p. 40° to 60° C)
- customcrystallised from petroleum ether (b.p. 60° to 80° C)/ ethyl acetate
출처 및 근거
- ORD 기록
- ord-239a5fa649b640afa3a2d6d118becc84
- 출처 데이터셋
- uspto-grants-1976_12
- 특허 번호
- US03998843
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