HCID 21490882, 화합물 → HCID 21490887, 화합물

HRID 1973893노트

반응식

HRID 1973893 반응식
C([O:4][CH2:5][C:6]1[CH:11]=[C:10]([Cl:12])[C:9]([CH2:13][CH2:14][CH2:15][CH3:16])=[C:8]([Cl:17])[N:7]=1)(=O)C>Cl>[OH:4][CH2:5][C:6]1[CH:11]=[C:10]([Cl:12])[C:9]([CH2:13][CH2:14][CH2:15][CH3:16])=[C:8]([Cl:17])[N:7]=1

참가 물질

3

반응물 1

HCID 21490882HCID 21490882, 화합물

생성물 1

HCID 21490887HCID 21490887, 화합물

시약·촉매·용매 1

HCID 313Hydrochloric Acid용매

실험 절차

40 g of 2-acetoxymethyl-4,6-dichloro-5-n-butyl-pyridine in 200 ml of 6 N hydrochloric acid are boiled for 15 hours under reflux. Thereafter the mixture is evaporated to dryness. The residue is taken up in chloroform and extracted by shaking with aqueous potassium carbonate solution. The chloroform solution is dried and evaporated. Fractional distillation yields 2-hydroxymethyl-4,6-dichloro-5-n-butyl-pyridine of boiling point 150°-160° (0.1 mm Hg).

후처리

  1. temperatureunder reflux
  2. customThereafter the mixture is evaporated to dryness
  3. extractionextracted
  4. dry with materialThe chloroform solution is dried
  5. customevaporated
  6. distillationFractional distillation

출처 및 근거

ORD 기록
ord-ddf36dc61d3843818b0cdcfe50d241a8
출처 데이터셋
uspto-grants-1976_12
특허 번호
US03998955

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