Acetone → HCID 21490924, 화합물
반응식
[OH:1][CH2:2][C:3]1[CH:8]=[C:7]([O:9][CH3:10])[C:6]([CH2:11][CH2:12][CH2:13][CH3:14])=[CH:5][N:4]=1.[ClH:15].CC(C)=O>CO.CCOCC>[ClH:15].[OH:1][CH2:2][C:3]1[CH:8]=[C:7]([O:9][CH3:10])[C:6]([CH2:11][CH2:12][CH2:13][CH3:14])=[CH:5][N:4]=1참가 물질
6
실험 절차
A solution of 2-hydroxymethyl-4-methoxy-5-n-butyl-pyridine in methanol is adjusted to pH 1 with hydrochloric acid in ether and evaporated to dryness. The water which still adheres is distilled off azeotropically with toluene. The residue thus obtained is digested with acetone and the crystalline product is filtered off. 2-Hydroxymethyl-4-methoxy-5-n-butyl-pyridine hydrochloride of melting point 136°-137° is thus obtained.
후처리
- customevaporated to dryness
- distillationThe water which still adheres is distilled off azeotropically with toluene
- customThe residue thus obtained
- filtrationthe crystalline product is filtered off
출처 및 근거
- ORD 기록
- ord-aeed5e8fff4941e58bb877b6c0ed57ff
- 출처 데이터셋
- uspto-grants-1976_12
- 특허 번호
- US03998955
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