Methylamine → HCID 19101480, 화합물

HRID 1974431노트

반응식

HRID 1974431 반응식
[CH3:1][NH2:2].Cl[CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][OH:13].[OH-].[Na+]>O>[CH3:1][NH:2][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][OH:13]

참가 물질

5

반응물 3

HCID 6329Methylamine2회HCID 14798Sodium HydroxideHCID 30849741-Nonanol, 9-chloro-

생성물 1

HCID 19101480HCID 19101480, 화합물

시약·촉매·용매 1

HCID 962Water용매

반응 조건

온도
100 °C

실험 절차

400 g a 40% aqueous solution of methylamine and 180 g of 9-chlorononanol were introduced into an autoclave equipped with a stirrer, a thermometer and a pressure pump and heated to 100° C. At the temperature, 93 g of a 48% aqueous solution of sodium hydroxide was forcedly introduced to the autoclave over 6 hours and the resulting mixture was aged for 1 hours. After cooling, the content was taken out from the autoclave and unreacted methylamine and water were removed therefrom under reduced pressure. Then, ethanol was added thereto and sodium chloride thus precipitated was filtered off. Ethanol was distilled off from the filtrate and the resulting solution was further subjected to distillation to give 125 g of 9-(N-methylamino)nonanol.

후처리

  1. customequipped with a stirrer
  2. temperatureAfter cooling
  3. customwere removed
  4. additionThen, ethanol was added
  5. customsodium chloride thus precipitated
  6. filtrationwas filtered off
  7. distillationEthanol was distilled off from the filtrate
  8. distillationthe resulting solution was further subjected to distillation

출처 및 근거

ORD 기록
ord-426abac6664346d6b4fd864a7f287fac
출처 데이터셋
uspto-grants-1994_02
특허 번호
US05282983

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