N-bromobutanimide → HCID 19101519, 화합물

HRID 1974439노트

반응식

HRID 1974439 반응식
[C:1](=[C:4]([C:9]([O:11][CH3:12])=[O:10])[C:5]([O:7][CH3:8])=[O:6])([CH3:3])[CH3:2].C1C(=O)N([Br:20])C(=O)C1>C(Cl)(Cl)(Cl)Cl>[C:1](=[C:4]([C:9]([O:11][CH3:12])=[O:10])[C:5]([O:7][CH2:8][Br:20])=[O:6])([CH3:3])[CH3:2]

참가 물질

4

반응물 2

HCID 67184N-bromobutanimideHCID 51620841,3-Dimethyl 2-(propan-2-ylidene)propanedioate

생성물 1

HCID 19101519HCID 19101519, 화합물수율 109.7%

시약·촉매·용매 1

HCID 5943Carbon Tetrachloride용매

실험 절차

A mixture of 26. 4 grams (0.15 mol) of dimethyl isopropylidenemalonate and 27.5 grams (0.15 mol) of n-bromosuccinimide were stirred in 150 mL carbon tetrachloride containing 1.0 grams benzoyl peroxide. The mixture was refluxed for 16 hours under nitrogen. The reaction was cooled in ice and the succinimide was filtered off and washed with carbon tetrachloride. The solvent was removed under reduced pressure to yield 41.3 grams of impure bromomethyl methyl isopropylidenemalonate as an oil which was used without further purification.

후처리

  1. temperatureThe mixture was refluxed for 16 hours under nitrogen
  2. temperatureThe reaction was cooled in ice
  3. filtrationthe succinimide was filtered off
  4. washwashed with carbon tetrachloride
  5. customThe solvent was removed under reduced pressure

출처 및 근거

ORD 기록
ord-d858b7c4856443bf821a86446567fecc
출처 데이터셋
uspto-grants-1994_02
특허 번호
US05283165

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