Water → HCID 18990361, 화합물

HRID 1974736노트

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HRID 1974736 반응식
[OH:1][C:2]1[CH:3]=[C:4]([CH:7]=[C:8]([N+:11]([O-:13])=[O:12])[C:9]=1[OH:10])[CH2:5]O.[NH:14]1[CH:18]=[CH:17][CH:16]=[CH:15]1.O>O1CCOCC1>[OH:1][C:2]1[CH:3]=[C:4]([CH:7]=[C:8]([N+:11]([O-:13])=[O:12])[C:9]=1[OH:10])[CH2:5][C:15]1[NH:14][CH:18]=[CH:17][CH:16]=1

참가 물질

5

반응물 3

HCID 962WaterHCID 8027PyrroleHCID 189903745-(Hydroxymethyl)-3-nitrobenzene-1,2-diol

생성물 1

HCID 18990361HCID 18990361, 화합물

시약·촉매·용매 1

HCID 312751,4-Dioxane용매

반응 조건

온도
100 °C

실험 절차

A solution containing 1.0 g of 3,4-dihydroxy-5-nitrobenzylalcohol and 5.0 ml of pyrrole in 3.0 ml of dioxane was heated for 5 h at 100° C. Water was added and the solution was extracted with dichloromethane. The solvent was evaporated and the residue was purified in a silicagel column using toluene-acetic acid-dioxane (18:1:1) mixture as an eluent. Yield 0.42 g (33%), m.p. 115°-118° C.

후처리

  1. extractionthe solution was extracted with dichloromethane
  2. customThe solvent was evaporated
  3. customthe residue was purified in a silicagel column

출처 및 근거

ORD 기록
ord-da548f3fbfa24705b69d57bf669feb24
출처 데이터셋
uspto-grants-1994_02
특허 번호
US05283352

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