Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrazine hydrate (1:1) → 4-Hydrazino-2-(trifluoromethyl)quinazoline
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrazine hydrate (1:1) | HCID 24654 | — |
| 반응물 | 4-Chloro-2-(trifluoromethyl)quinazoline | HCID 1475435 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | 4-Hydrazino-2-(trifluoromethyl)quinazoline | HCID 1475464 | — |
반응 단계
4-Chloro-2-trifluoromethylquinazoline (46.4 g, 0.2 mole) was taken up in ethanol (500 ml). Hydrazine hydrate (20 ml, 0.4 mole) was added and the contents refluxed for 2 hours. On cooling, the yellow precipitate was filtered and slurried in water (500 ml) to removed hydrazine hydrochloride. Filtration gave the product as a yellow crystalline solid, 34.5 g (76%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05284739 |
| 출처 데이터셋 | uspto-grants-1994_02 |
| ORD ID | ord-660c1964dfcd4fa88cf7408a28da8c43 |
| 출처 메모 | uspto-grants-1994_02 |