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Azobisisobutyronitrile → Propyl maleimide t-butyl 5-norbornene-2-carboxylate 2-hydroxyethyl bicyclo[2,2,2]oct-5-ene-2-carboxylate

HRID 1975892
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HRID 1975892 반응식
[CH2:1]([C:4]1[C:5]([NH:7][C:8](=[O:10])[CH:9]=1)=[O:6])[CH2:2][CH3:3].[CH:11]12[CH2:17][CH:14]([CH:15]=[CH:16]1)[CH2:13][CH:12]2[C:18]([O:20][C:21]([CH3:24])([CH3:23])[CH3:22])=[O:19].[CH:25]12[CH2:32][CH2:31][CH:28]([CH:29]=[CH:30]1)[CH2:27][CH:26]2[C:33]([O:35][CH2:36][CH2:37][OH:38])=[O:34].N(C(C)(C)C#N)=NC(C)(C)C#N>O1CCCC1>[CH2:1]([C:4]1[C:5]([NH:7][C:8](=[O:10])[CH:9]=1)=[O:6])[CH2:2][CH3:3].[CH:11]12[CH2:17][CH:14]([CH:15]=[CH:16]1)[CH2:13][CH:12]2[C:18]([O:20][C:21]([CH3:24])([CH3:23])[CH3:22])=[O:19].[CH:25]12[CH2:32][CH2:31][CH:28]([CH:29]=[CH:30]1)[CH2:27][CH:26]2[C:33]([O:35][CH2:36][CH2:37][OH:38])=[O:34]
참가 물질실험 절차후처리출처 및 근거반응 노트

참가 물질

6

반응물 4

HCID 6547AzobisisobutyronitrileHCID 15607334Bicyclo[2.2.1]hept-5-ene-2-carboxylic acid, 1,1-dimethylethyl esterHCID 184136662-Hydroxyethyl bicyclo[2,2,2]oct-5-ene-2-carboxylateHCID 21880478Propyl maleimide

생성물 1

HCID 86756650Propyl maleimide t-butyl 5-norbornene-2-carboxylate 2-hydroxyethyl bicyclo[2,2,2]oct-5-ene-2-carboxylate수율 79%

시약·촉매·용매 1

HCID 8028Tetrahydrofuran용매

실험 절차

Propyl maleimide (1 mol.), t-butyl 5-norbornene-2-carboxylate (0.5 mol.) and 2-hydroxyethyl bicyclo[2,2,2]oct-5-ene-2-carboxylate (0.5 mol) were dissolved in 50 g to 300 g of tetrahydrofuran (THF), 2 g to 15 g of 2,2′-azobisisobutyronitrile (AIBN) was added thereto, and the resulting solution was reacted at a temperature between 60° C. and 70° C. in a nitrogen atmosphere for 10 hours. After a high molecular weight was achieved by the reaction, the resultant product was precipitated in an ethyl ether or hexane solvent. The gathered precipitate was dried, and the desired poly(propyl maleimide/t-butyl 5-norbornene-2-carboxylate/2-hydroxyethyl bicyclo[2,2,2]oct-5-ene-2-carboxylate) polymer was obtained at a yield of about 79%.

후처리

  1. customthe resulting solution was reacted at a temperature between 60° C. and 70° C. in a nitrogen atmosphere for 10 hours
  2. customAfter a high molecular weight was achieved by the reaction
  3. customthe resultant product was precipitated in an ethyl ether or hexane solvent
  4. customThe gathered precipitate was dried
  5. customwas obtained at a yield of about 79%

출처 및 근거

ORD 기록
ord-2030d416a3724060b71fe12ef757e3f0
출처 데이터셋
uspto-grants-2001_05
DOI
10.6084/m9.figshare.5104873.v1
특허 번호
US06225020B1

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