Iodoethane → HCID 178477485, 화합물

HRID 1975902노트

반응식

HRID 1975902 반응식
[O:1]([C:8]1[CH:13]=[CH:12][C:11]([NH:14][C:15]([NH2:17])=[S:16])=[CH:10][CH:9]=1)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.[I:18][CH2:19][CH3:20]>CC(C)=O>[IH:18].[CH2:19]([S:16][C:15](=[NH:17])[NH:14][C:11]1[CH:12]=[CH:13][C:8]([O:1][C:2]2[CH:3]=[CH:4][CH:5]=[CH:6][CH:7]=2)=[CH:9][CH:10]=1)[CH3:20]

참가 물질

4

반응물 2

HCID 6340IodoethaneHCID 27603494-Phenoxyphenylthiourea

생성물 1

HCID 178477485HCID 178477485, 화합물

시약·촉매·용매 1

HCID 180Acetone용매

실험 절차

To a stirred solution of 1-(4-phenoxyphenyl)-2-thiourea (2.00 g, 8.19 mmol) in acetone (20 ml) was added iodoethane (7.61 g, 48.7 mmol). The mixture was heated to reflux for three hours, cooled to room temperature and concentrated at reduced pressure. The resulting viscous oil was crystallized from acetone-pentane to afford S-ethyl-N-(4-phenoxyphenyl)isothiourea hydroiodide as a beige solid. Mp=140-143° C.

후처리

  1. temperatureThe mixture was heated
  2. temperatureto reflux for three hours
  3. concentrationconcentrated at reduced pressure
  4. customThe resulting viscous oil was crystallized from acetone-pentane

출처 및 근거

ORD 기록
ord-bc9406f2ad1d4b459e5b1ff78e25e25c
출처 데이터셋
uspto-grants-2001_05
특허 번호
US06225305B1

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