Tetrahydrofurfuryl alcohol → HCID 21997501, 화합물

HRID 1977260노트

반응식

HRID 1977260 반응식
[CH3:1][O:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][O:9][C:10]1[CH:19]=[CH:18][C:13]([C:14](OC)=[O:15])=[CH:12][CH:11]=1.O1CCCC1CO.O.[NH2:28][NH2:29]>O>[CH3:1][O:2][CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][O:9][C:10]1[CH:19]=[CH:18][C:13]([C:14]([NH:28][NH2:29])=[O:15])=[CH:12][CH:11]=1

참가 물질

5

반응물 3

HCID 7360Tetrahydrofurfuryl alcoholHCID 24654Hydrazine hydrate (1:1)HCID 21997570HCID 21997570, 화합물

생성물 1

HCID 21997501HCID 21997501, 화합물

시약·촉매·용매 1

HCID 962Water용매

실험 절차

A solution of methyl 4-(6-methoxy-n-hexyloxy)benzoate (17.05 g) in 1:1 tetrahydrofuran-methanol (300 ml) was treated with hydrazine monohydrate (66 ml) and refluxed for 15 hours then cooled to room temperature. The reaction mixture was poured into water and the resulting precipitate collected by filtration, washed thoroughly with water then dried under hi-vacuum at 50° C. to give 4-(6-methoxy-n-hexyloxy)benzohydrazide (15.63 g) as a white solid.

후처리

  1. temperaturerefluxed for 15 hours
  2. filtrationthe resulting precipitate collected by filtration
  3. washwashed thoroughly with water
  4. customthen dried under hi-vacuum at 50° C.

출처 및 근거

ORD 기록
ord-f1541a554f834b3c85aee3faaf5f3224
출처 데이터셋
uspto-grants-2001_05
특허 번호
US06232290B1

반응 노트

불러오는 중…