Sodium Hydroxide → HCID 712932, 화합물

HRID 1977288노트

반응식

HRID 1977288 반응식
FC(F)(F)C(O)=O.C[O:9][C:10](=[O:23])[C:11]1[CH:16]=[CH:15][C:14]([C:17]2[S:18][C:19]([NH2:22])=[N:20][N:21]=2)=[CH:13][CH:12]=1.[OH-].[Na+]>O>[NH2:22][C:19]1[S:18][C:17]([C:14]2[CH:13]=[CH:12][C:11]([C:10]([OH:23])=[O:9])=[CH:16][CH:15]=2)=[N:21][N:20]=1

참가 물질

4

반응물 2

HCID 14798Sodium HydroxideHCID 70053962HCID 70053962, 화합물

생성물 1

HCID 712932HCID 712932, 화합물수율 99.7%

시약·촉매·용매 1

HCID 962Water용매

실험 절차

To a solution of 4-(5-amino-1,3,4-thiadiazol-2-yl)benzoic acid methyl ester trifluoroacetic acid salt (8 g) in water was added 1N sodium hydroxide and the mixture was adjusted to pH 8. The precipitate was collected by filtration to give 4-(5-amino-1,3,4-thiadiazol-2-yl)benzoic acid (5.05 g).

후처리

  1. filtrationThe precipitate was collected by filtration

출처 및 근거

ORD 기록
ord-46f2294dd12648d88ddd4544db7fcdd9
출처 데이터셋
uspto-grants-2001_05
특허 번호
US06232290B1

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